General Sites:

Schools and Universities:
University of Reddit with corresponding subreddit
MIT Lectures
Carnegie Mellon
Johns Hopkins
Tufts
Rice - Connexions
Utah State
Berkeley
Berkeley Part 2
Berkeley Part 3 (videos)
Stanford
Stanford Part 2 (videos)
Harvard
University of Sydney
University of Virginia
Stanford
Yale
Yale Part 2 (videos)
University of Chicago
University of New South Wales
Open Course Ware Finder
Open Course Ware Consortium
University of the People
P2P University - "Learn anything with your peers" (recommended by johndbritton via PM)

Other General Sites:
OpenStudy - This site is highly recommended. The CEO is a fellow redditor and all around nice guy. OpenStudy is partnered with such institutions as MIT OpenCourseWare and Yale Open Course, and includes 80,000 users from 1600 schools. For more info, check out this TechCrunch.com article. (recommended via PM)

Wikiversity

Youtube Edu

100 Best Intro Courses

Khan Academy

Open Culture

TED

Cosmo Learning

Knol

Academic Earth

Free Video Lectures

More Video Lectures

Directory of Open Access Journals

Learners TV

IncrediCampus

LectureFox

Freelance-Teacher

National Programme on Tech Enhanced Learning

Study Blue

WikiHow

How Stuff Works

Wonder How To

Better Explained

TeachMate

Learning Schedule Tracker - Smart.fm

Mixergy - "Where entrepreneurs teach" requires E-mail address (recommended by AndrewWarner via PM)



Specialized Sites:

Computer Related:
Carl H Programming with corresponding subreddit
Google Code University
The New Boston - Step by step lessons for multiple languages (recommended by Exano and Dsch1ngh1s_Khan via PM)
Learn about Linux
Free Technology Academy
University of Washington CSE
Lynda.com
Web Building Tutorials
Building Websites via Academic Earth
Opera Web Standards Curriculum
Stack Overflow (Question Site)
D Zone (Question Site)
VideoCoPilot - Tutorials for Adobe After Effects (recommended by Dsch1ngh1s_Khan via PM)
Nettuts - Web development tutorials (recommended by Malpercio via PM)
Bloc - "Bloc makes it easy and fun to learn how to program" (recommended by scrappy D00 via PM)

Music:
Teoria - Classical Music Theory (recommended by WhatYouGive via PM)
Funk University
Piano Lessons
Music Theory - Trainear.com
Music Theory - MusicTheory.net
Guitar Lessons at Ultimate-Guitar
Guitar Lessons at The Stringery
Guitar Lessons at The Next Level Guitar
Guitar Lessons at Justin Guitar
Bass Lessons
Chord Book - Chordbook.com
Chord Book - Chorder.com
Guitar Neck Quiz

Language:
LiveMocha
Languages from BBC
FSI Language Courses
Duolingo - "Learn language for free and translate the web" (recommended by TychePsyche via PM with associated TED Talk)
Talk To Me In Korean - a website for lessons on speaking Korean (very highly recommended by biscuitlol via PM)

Cooking/Food:
Good...